Publications by authors named "J B Waldman"
Current Practice Management Guidelines in Neonates and Infants with Isolated Coarctation of the Aorta.
J Cardiothorac Vasc Anesth
December 2024
Article Synopsis
- Metastatic disease is a major cause of cancer-related deaths, yet its tumor microenvironment is not well understood due to technical challenges in studying it.
- This research created a comprehensive map of 67 tumor biopsies from 60 metastatic breast cancer patients, using advanced techniques like single-cell RNA sequencing and various spatial expression assays to analyze tumor characteristics.
- Key findings included identifying different macrophage spatial patterns, three phenotypes of epithelial-to-mesenchymal transition, and gene expression linked to T cell presence or absence, highlighting the study's potential for clinical insights.
The Society of Thoracic Surgeons Congenital Heart Surgery Database: 2023 Update on Outcomes and Research.
J Cardiothorac Vasc Anesth
October 2024
Flexible electrode materials, particularly indium tin oxide (ITO)-coated polyethylene terephthalate (PET), have attracted the attention of researchers for a wide variety of applications. However, there has been limited attention to the effects of electrode flexibility during electrochemical processes. In this research article, we studied how bending commercially available ITO-PET electrodes impacts the electrodeposition process of polyaniline (PANI).
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- - Diabetic kidney disease (DKD) is a major cause of kidney failure linked to diabetes and obesity, but effective treatments to slow its progression are currently unavailable.
- - Research on single-cell transcriptomic profiles from DKD patients and mouse models reveals a growing population of macrophages expressing TREM2 in mice fed a high-fat diet, which correlates with obesity and diabetes.
- - In mice lacking TREM2, increased kidney damage and cell injury were observed, indicating that boosting TREM2 macrophages could be a promising therapeutic approach for DKD.