Publications by authors named "J B Wade"

Introduction: The utility of pancreaticoduodenectomy (PD) for high-grade traumatic injuries remains unclear and data surrounding its use are limited. We hypothesized that PD does not result in improved outcomes when compared with non-PD surgical management of grade IV-V pancreaticoduodenal injuries.

Methods: This is a retrospective, multicenter analysis from 35 level 1 trauma centers from January 2010 to December 2020.

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The sociodemographic makeup of the professoriate in health and healthcare has been shown to have direct implications for graduation rates among minoritized populations, diversity in healthcare, the prevalence of health equity scholarship, and population health broadly. Black women academics, who navigate higher education as members of two minoritized groups, need to be intentionally recruited and retained using tailored approaches. Given the historical and ongoing dearth of Black women faculty in health and healthcare, and the mounting literature on health equity highlighting the benefits of Black women representation in healthcare, I propose an approach to the recruitment and retention of Black women using a Black feminist theory.

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Background: Although the challenges of recruiting to randomised controlled trials (RCTs) are well documented, few studies have focused on the impact that the communication between recruiters and patients has on patients' participation decisions. Recruiters are thought to influence patient decision-making, but the mechanisms by which this occurs are unclear. The aim of this research was to investigate how patients interpret and use the information conveyed to them by healthcare professionals (HCPs) in trial participation decisions.

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Article Synopsis
  • Aggregation of antimicrobial peptides (AMPs) can increase their effectiveness against bacteria by disrupting their cell structures, presenting a potential solution to antibiotic resistance.
  • Researchers focused on the cephalopod Octopus bimaculoides, which lacks known AMP genes, and utilized artificial intelligence to identify four aggregation-prone peptides (Oct-P1 to Oct-P4), with Oct-P2 showing a 90% reduction in bacterial viability.
  • The study revealed that Oct-P2 not only penetrates bacterial cells but also interacts with DNA, hindering gene expression, thus illustrating its promise as a template for developing new antimicrobial therapies.
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