Publications by authors named "J B Spies"
Background And Aims: Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is difficult to distinguish from mimicking disorders, with misdiagnosis resulting in IVIG overutilization. We evaluate a clinical-electrophysiological model to facilitate CIDP versus mimic neuropathy prediction.
Methods: Using the European Academy of Neurology/Peripheral Nerve Society (EAN/PNS) 2021 CIDP guidelines we derived 26 clinical and 144 nerve conduction variables.
Solid-state high harmonic generation (sHHG) spectroscopy is an emerging ultrafast technique for studying key material properties such as electronic structure at and away from equilibrium. sHHG anisotropy measurements, where sHHG spectra are recorded depending on the driving electric field relative to the crystal lattice, have become a powerful tool for studying crystal symmetries. Previous works on two-dimensional materials and other quantum materials have often used substrate-supported samples, assuming that all sHHG signals originate from the sample due to the relatively large bandgap of the substrate.
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- The study focuses on sequencing and annotating the genome of the sacoglossan sea slug Elysia timida, a species that can store chloroplasts from its food algae, in order to improve understanding of genome architecture and evolution in molluscs.
- The researchers achieved a high-quality chromosome-level genome assembly using advanced techniques, resulting in higher scaffold and contig N50s than previous sacoglossan genomes, alongside the identification of nearly 20,000 protein-coding genes.
- Findings also indicated that while no horizontal gene transfer was detected, the presence of polyketide synthase genes suggests the production of polypropionates, highlighting the unique biochemical capabilities of this sea slug.
Populations of various economic species of wireworms are increasing in the key cereal crop production areas of Canada and the United States. To address this problem, seed treatments are under development that both provide crop protection and significantly reduce populations equivalent in effectiveness to the formerly used but now deregistered organochlorine lindane. Herein, we evaluated isocycloseram (PLINAZOLIN technology), the first isoxazoline (GABA-gated Chloride Channel Allosteric Modulator) agricultural insecticide, as a seed treatment for the protection of cereal crops from the sugarbeet wireworm, Limonius californicus (Mannerheim).
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