Risk factors for non-compliance of patient reported outcome measures following achilles tendon repair surgery.

Background: Patient-Reported Outcome Measures (PROMs) are increasingly utilized in orthopaedic research and assess the patient's response to care, allow for assessment of the patient's overall health, and provide tools to promote the shared decision-making process. Our hypothesis is that risk factors for non-compliance is increasing age and increasing time after surgery.

Methods: PROMs compliance was conducted from survey data of 90 individuals from May 2017 to July 2023 who had Achilles tendon surgery.

Demographic Characteristics and Prescription Drug Histories of Unintentional Overdose Decedents in Philadelphia, PA.

Background: Philadelphia's opioid overdose crisis has reached unprecedented levels. However, overdose deaths involving non-opioids have also increased in recent years. As overdose deaths continue to increase, this study describes and compares the demographic characteristics, prescription drug histories, and exposure to potentially inappropriate prescribing practices (PIPPs), in the year before death of three groups of overdose decedents: (1) only opioid(s) detected in postmortem toxicology, (2) only non-opioid(s) detected, (3) both opioids and non-opioids co-detected [i.

Whale baleen to monitor per- and polyfluoroalkyl substances (PFAS) in marine environments.

Per- and polyfluoroalkyl substances (PFAS) comprise > 10,000 synthetic compounds that are globally distributed and highly persistent but remain challenging to monitor. Here we assess the utility of baleen-an accreting, keratinaceous tissue that baleen whales use for filter-feeding-to track PFAS dynamics in marine food webs. In six species investigated, PFAS were detected in all baleen tested (n = 18 plates, 220 samples, ΣPFAS range 0.

Hedgehog signaling directs cell differentiation and plays a critical role in tendon enthesis healing.

A high prevalence of rotator cuff tears presents a major clinical challenge. A better understanding of the molecular mechanisms underlying enthesis development and healing is needed for developing treatments. We recently identified hedgehog (Hh)-lineage cells critical for enthesis development and repair.

Trends in Demographic, Clinical, Socioeconomic, and Facility-Specific Factors Linked to Eyelid Melanoma Survival: A National Cancer Database Analysis.

Purpose: This study aimed to analyze demographic, clinical, socioeconomic, and facility-specific factors affecting the survival outcomes of patients diagnosed with eyelid melanoma (EM) between 2004 and 2017 using data from the National Cancer Database.

Methods: Cases of EM diagnosed between 2004 and 2017 were identified using the National Cancer Database. Patient demographic data, tumor stage (American Joint Committee on Cancer TNM classification), treatment modalities, and socioeconomic variables were collected.