Analyses of the Genetic Diversity and Population Structures of spp. Clinical Isolates from Paraíba, Brazil.

Unlabelled: Sporotrichosis is a subcutaneous mycosis of global distribution, capable of affecting both humans and animals, and caused by species of the genus spp. This study aimed to evaluate the genetic diversity and mating type distribution of clinical isolates of human sporotrichosis in Paraíba, Brazil, to better understand the population structure, epidemiology, and diversification of this pathogen, as well as to explore possible transmission routes.

Methods: A total of 36 clinical isolates were morphologically identified, and clinical and demographic data were collected.

Domestic and external violence, parental neglect, and social sanctions among crack users: A cross-sectional study exploring the role of gender.

Background: Substance Use Disorders are often associated with significant levels of domestic and external violence registered among abusers. This investigation aimed to evaluate the Domestic Violence Involvement (DVI) and related gender differences among Crack Cocaine Users in Brazil.

Methods: For this purpose, a secondary data analysis of a multicenter cross-sectional study involving 780 Crack Cocaine Users from 6 Brazilian capitals was performed.

Pseudo-Sciatica Pain Due to a Biceps Femoris Muscle Tear.

Hamstring injuries (HSIs) are common among athletes, particularly in high-speed sports, and are frequently associated with prolonged recovery periods and a high recurrence rate. This study presents a 36-year-old male with sciatica-like symptoms following an acute hamstring tear during an amateur football match. The patient experienced this pain two weeks after the injury, suggesting potential sciatic nerve involvement.

The Mediating Role of Sexual Boredom in Women's Sexual Desire and Satisfaction.

Sexual boredom in women is associated with various levels and dimensions of sexual desire, as well as lower sexual and relationship satisfaction. However, the directionality of these relationships remains unclear. This study aimed to investigate whether sexual boredom mediates the relationship between partner and attractive-other sexual desire and sexual and relationship satisfaction in a sample of 1155 Portuguese women in long-term monogamous relationships.

Aging promotes an increase in mitochondrial fragmentation in astrocytes.

Introduction: Brain aging involves a complex interplay of cellular and molecular changes, including metabolic alterations and the accumulation of senescent cells. These changes frequently manifest as dysregulation in glucose metabolism and mitochondrial function, leading to reduced energy production, increased oxidative stress, and mitochondrial dysfunction-key contributors to age-related neurodegenerative diseases.

Methods: We conducted experiments on two models: young (3-4 months) and aged (over 18 months) mice, as well as cultures of senescent and control mouse astrocytes.