Publications by authors named "J B Oldemeyer"

Background: For patients with asymptomatic severe aortic stenosis and preserved left ventricular ejection fraction, current guidelines recommend routine clinical surveillance every 6 to 12 months. Data from randomized trials examining whether early intervention with transcatheter aortic-valve replacement (TAVR) will improve outcomes in these patients are lacking.

Methods: At 75 centers in the United States and Canada, we randomly assigned, in a 1:1 ratio, patients with asymptomatic severe aortic stenosis to undergo early TAVR with transfemoral placement of a balloon-expandable valve or clinical surveillance.

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Article Synopsis
  • Transcatheter aortic valve implantation (AViV) was studied in 100 low- and intermediate-risk patients with bioprosthetic valve failure, focusing on safety and effectiveness over a year.
  • Primary outcomes showed a very low rate of complications, with only 2.1% experiencing strokes and no deaths within the year.
  • Significant improvements were observed in patient health metrics, such as reduced functional class and lower heart valve pressure gradients, indicating that AViV could be a viable treatment option for this patient group, pending further long-term studies.
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Background: Serum troponin levels correlate with the extent of myocyte necrosis in acute myocardial infarction (AMI) and predict adverse outcomes. However, thresholds of cardiac troponin elevation that could portend to poor outcomes have not been established.

Methods: In this cohort study, we characterized all cardiac troponin elevations > 0.

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Objectives: This study sought to determine the safety of the BASILICA (bioprosthetic or native aortic scallop intentional laceration to prevent iatrogenic coronary artery obstruction) procedure.

Background: Transcatheter aortic valve replacement causes coronary artery obstruction in 0.7% of cases, with 40% to 50% mortality.

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Patient Presentation: We report the case of a 66 year old female who presented to our institution fourteen years after receiving a St. Jude Mechanical Mitral Valve Replacement. She presented in refractory NYHA class IV congestive heart failure with comorbidities of acute renal failure, liver failure, and mental status changes.

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