Publications by authors named "J B Muilwijk-Kroes"

Article Synopsis
  • Symptoms of asthma and COPD can be similar, and patients may have both conditions simultaneously, indicating a need for better assessment tools.
  • The study aimed to develop a new questionnaire by combining the asthma control questionnaire (ACQ) and the clinical COPD questionnaire (CCQ) to evaluate disease burden across all obstructive lung diseases.
  • Using data from various patient cohorts, researchers identified nine key questions through Principal Component Analysis (PCA), leading to the proposed "Obstructive Lung Disease Questionnaire" for more effective disease assessment.
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Many asthmatics in primary care have mild symptoms and lack airflow obstruction. If variable expiratory airflow limitation cannot be determined by spirometry or peak expiratory flow, despite a history of respiratory symptoms, a positive bronchial challenge test (BCT) can confirm the diagnosis of asthma. However, BCT is traditionally performed in secondary care.

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The aim of this study was to develop and explore the diagnostic accuracy of a decision tree derived from a large real-life primary care population. Data from 9297 primary care patients (45% male, mean age 53±17 years) with suspicion of an obstructive pulmonary disease was derived from an asthma/chronic obstructive pulmonary disease (COPD) service where patients were assessed using spirometry, the Asthma Control Questionnaire, the Clinical COPD Questionnaire, history data and medication use. All patients were diagnosed through the Internet by a pulmonologist.

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