Publications by authors named "J B MINOR"
Background: Management of blunt splenic trauma has evolved over several decades, trending towards nonoperative management and splenic artery embolization. Extensive research has been conducted regarding the management of blunt splenic injuries, but there is little data on the association of treatment modality with discharge disposition.
Methods: This is an observational retrospective study conducted at a level-one trauma center with blunt splenic trauma patients of age ≥18 years between January 2010 and December 2021.
Background: Patients with cardiogenic shock or end-stage heart failure can be maintained on mechanical circulatory support (MCS) devices. Once a patient undergoes placement of a device, obtaining and maintaining therapeutic anticoagulation is vital. Guidelines recommend the use of institutional protocols to assist in dosing and titration of anticoagulants.
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- The study investigates a new PRDM5 gene variant linked to brittle cornea syndrome (BCS) in three siblings from a Laotian family, detailing their ophthalmic symptoms like myopia and thin corneas.
- All three children were found to be homozygous for the PRDM5 variant, and the youngest underwent a corneal transplant due to severe issues, with histopathology showing significant corneal damage.
- Findings suggest that the novel PRDM5 variant likely causes the observed BCS symptoms, with the surgical challenges also highlighted due to the fragility of the affected tissues.
The relationship between the congenital defect of gastroschisis and environmental toxins is poorly understood. We examined gastroschisis incidence, risk factors, and spatial association in a geographic region with known environmental pollution and hazardous waste sites. An observational study of fetal and neonatal gastroschisis diagnosed from 1/1/2006 to 12/31/2020 was conducted in a southern West Virginia (WV) tertiary care hospital.
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- Old trees play crucial ecological and cultural roles, but understanding their survival in areas affected by human activities is still limited.
- Using a massive database of nearly 1.8 million old trees from China, the study identified key species traits, such as height and leaf size, that predict long-term survival in urbanized environments.
- The research highlighted that species linked to human use thrive in heavily cultivated regions, whereas wild species are more resilient in mountainous areas, showing how different species react to human influence and environmental conditions.