Periparturient mortality in merino ewes in Australia: Incidence, impact and the path to mitigation strategies.

Managing breeding ewe mortality is a priority for the Australian sheep industry. The periparturient period carries the highest risk of mortality, but the incidence and causes in Merino ewes are not well characterised. Here, we outline the reported incidence of annual and periparturient mortality for Australian Merino ewes, causes and risk factors for ewe mortality and current recommendations for managing periparturient ewes and gaps in the literature.

Group arts interventions for depression and anxiety among older adults: a systematic review and meta-analysis.

In this systematic review and meta-analysis, we assessed the efficacy of group arts interventions, where individuals engage together in a shared artistic experience (for example, dance or painting), for reducing depression and anxiety among older adults (> 55 yr without dementia). Fifty controlled studies were identified via electronic databases searched to February 2024 (randomised: 42, non-randomised: 8). Thirty-nine studies were included.

A multifaceted intervention to improve diagnosis and early management of hospitalised patients with suspected acute brain infections in Brazil, India, and Malawi: an international multicentre intervention study.

Background: Brain infections pose substantial challenges in diagnosis and management and carry high mortality and morbidity, especially in low-income and middle-income countries. We aimed to improve the diagnosis and early management of patients admitted to hospital (adults aged 16 years and older and children aged >28 days) with suspected acute brain infections at 13 hospitals in Brazil, India, and Malawi.

Methods: With hospital stakeholders, policy makers, and patient and public representatives, we co-designed a multifaceted clinical and laboratory intervention, informed by an evaluation of routine practice.

Changes in unmet needs after treatment for head and neck cancers - A prospective longitudinal cohort study.

Objectives: This study aimed to assess changes in unmet needs among patients with head and neck cancer (HNC) from pre-treatment to two years post-treatment and identify factors associated with higher levels of unmet needs.

Materials & Methods: Patients treated for HNC at Princess Margaret Cancer Centre between June 2016 and February 2019 were recruited. Participants completed the Cancer Survivors' Unmet Needs Measure Questionnaire (CaSUN), the Functional Assessment of Cancer Therapy - Head and Neck (FACT-HN) questionnaire, and the EuroQol EQ-5D-5L utility and Visual Analog Scale (EQ-5D-5L and VAS) pre-treatment and at 3, 6, 12, and 24-months post-treatment.

Creation of Scientific Response Documents for Addressing Product Medical Information Inquiries: Mixed Method Approach Using Artificial Intelligence.

Background: Pharmaceutical manufacturers address health care professionals' information needs through scientific response documents (SRDs), offering evidence-based answers to medication and disease state questions. Medical information departments, staffed by medical experts, develop SRDs that provide concise summaries consisting of relevant background information, search strategies, clinical data, and balanced references. With an escalating demand for SRDs and the increasing complexity of therapies, medical information departments are exploring advanced technologies and artificial intelligence (AI) tools like large language models (LLMs) to streamline content development.