Publications by authors named "J B Jolly"
Charles Bonnet syndrome (CBS) is a condition characterised by visual hallucinations of varying complexity on a background of vision loss. CBS research has gained popularity only in recent decades, despite evidence dating back to 1760. Knowledge of CBS among both the patient and professional populations unfortunately remains poor, and little is known of its underlying pathophysiology.
View Article and Find Full Text PDFPFAS surveillance within a highly militarized island: a case study of Okinawa, Japan.
Environ Sci Process Impacts
December 2024
Article Synopsis
- PFAS are a group of over 12,000 synthetic chemicals commonly found in industrial, consumer, and food packaging products, raising environmental concerns due to their persistence.
- The study conducted on Okinawa Island, where U.S. military activities might contribute to PFAS contamination, involved sampling surface water at 61 locations to assess PFAS presence.
- Results revealed the detection of 15 different PFAS compounds, with varying concentrations across locations, highlighting significant pollution "hotspots" and indicating multiple sources of contamination in the region.
Purpose: Understanding test-retest variability (TRV) of mesopic microperimetry is critical for defining meaningful treatment effects in retinitis pigmentosa (RP) trials. This study uniquely evaluates intra- and intervisit TRV and coefficients of repeatability (CoRs) for microperimetry parameters in RP patients with varying best-corrected visual acuity (BCVA) levels.
Methods: In this single-centre prospective cohort study, RP patients were assessed on two visits, 14.
Purpose: The purpose of this study was to provide a large, multi-center normative dataset for the Macular Integrity Assessment (MAIA) microperimeter and compare the goodness-of-fit and prediction interval calibration-error for a panel of hill-of-vision models.
Methods: Microperimetry examinations of healthy eyes from five independent study groups and one previously available dataset were included (1137 tests from 531 eyes of 432 participants [223 women and 209 men]). Linear mixed models (LMMs) were fitted to the data to obtain interpretable hill-of-vision models.
Background: Charles Bonnet syndrome (CBS) is a condition in which people with vision loss experience complex visual hallucinations. These complex visual hallucinations may be caused by increased excitability in the visual cortex that are present in some people with vision loss but not others.
Objectives: We aimed to evaluate the association between γ-aminobutyric acid (GABA) in the visual cortex and CBS.