Publications by authors named "J B Glaser"

The disadvantaged populations eGFR (estimated glomerular filtration rate) epidemiology (DEGREE) study was designed to gain insight into the burden of chronic kidney disease (CKD) of undetermined cause (CKDu) using standard protocols to estimate the general-population prevalence of low eGFR internationally. Therefore, we estimated the age-standardized prevalence of eGFR under 60 ml/min per 1.73m in adults aged 18-60, excluding participants with commonly known causes of CKD; an ACR (albumin/creatinine ratio) over 300 mg/g or equivalent, or self-reported or measured (HT) hypertension or (DM) diabetes mellitus, stratified by sex and location.

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Unlabelled: In the summer season, road construction workers perform physically demanding tasks outdoors, placing them at greater risk for exertional heat illness conditions. Assessing core temperature (Tcore) is critical as it serves as a key indicator of heat strain and helps to estimate the risk of heat-related illness. Despite the increased risk of hyperthermia, previous research has not assessed Tcore in road construction workers in the United States during summer work.

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Traumatic injury remains a leading cause of death globally, necessitating rapid and accurate diagnostic tools in emergency settings. Whole-body computed tomography (WBCT) has emerged as an increasingly utilized component in trauma care due to its speed and diagnostic precision. This review summarizes current data on the impact of WBCT on trauma mortality and examines the frequency and clinical implications of incidental findings (IFs).

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Article Synopsis
  • The DEGREE study explored the impact of chronic kidney disease of undetermined cause (CKDu) globally by analyzing the prevalence of low estimated glomerular filtration rate (eGFR) in adults aged 18-60, focusing on participants without known CKD causes.
  • The study included data from 60,964 participants across 43 areas in 14 countries collected from 2007 to 2023, revealing the highest CKDu prevalence in rural areas of Uddanam, India, and Northwest Nicaragua (14%).
  • The findings indicate that CKDu is notably prevalent in specific regions, especially within Central America and South Asia, prompting the need for global monitoring while acknowledging the potential existence of unidentified disease clusters elsewhere.
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