Exercise referral schemes (ERS) involving referrals from primary care providers to exercise programs and professionals may be a useful strategy for helping patients lead more active lifestyles. We performed an umbrella review to determine the impact of ERS on patient activity/fitness, clinical outcomes, and their cost-effectiveness. The review was pre-registered in Prospero (CRD42023443094) and conducted in July 2023.
View Article and Find Full Text PDFRegul Toxicol Pharmacol
September 2024
Allyl alcohol (C3H6O; prop-2-en-1-ol; CAS RN 107-18-6; EINECS 203-470-7) is used as an intermediate/monomer in polymerization reactions producing chemicals/optical resins or as a coupling/cross-linking agent for unsaturated polyester and alkyd resins. Human exposure to allyl alcohol (AA) is restricted to workplace manufacturing facilities where it is used in enclosed systems, which limits release and impact on environmental receptors. To address regulatory questions about possible developmental toxicity, two OECD Guideline studies were conducted.
View Article and Find Full Text PDFThe outbreak of e-cigarette or vaping use-associated lung injury (EVALI) in the United States in 2019 led to a total of 2807 hospitalizations with 68 deaths. While the exact causes of this vaping-related lung illness are still being debated, laboratory analyses of products from victims of EVALI have shown that vitamin E acetate (VEA), an additive in some tetrahydrocannabinol (THC)-containing products, is strongly linked to the EVALI outbreak. Because of its similar appearance and viscosity to pure THC oil, VEA was used as a diluent agent in cannabis oils in illicit markets.
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