Evidence of Magnetic Reconnection in Ganymede's Wake Region From Juno.

Magnetic reconnection has been commonly reported between the solar wind IMF and the magnetic field of Earth and other planets. A similar phenomenon is expected between Jupiter's magnetosphere and Ganymede's mini magnetosphere inside the Jovian magnetosphere. This article is the first report of a reconnection event in the tail region of Ganymede.

An overview of the currently available and emerging long-acting formulations of risperidone for schizophrenia and bipolar disorder.

Introduction: Long-acting injectable (LAI) antipsychotic medications can help improve treatment adherence in patients with schizophrenia and bipolar disorder. Despite this, they are underutilized. In 2003, intramuscular risperidone became the first available LAI atypical antipsychotic medication, and since then, a number of competing long-acting risperidone formulations have been brought to market, with additional options under active development.

Efficacy of HP-3070, A Once-Daily Asenapine Transdermal System, in the Treatment of Adults with Schizophrenia: A PANSS Five-Factor Analysis.

Introduction: HP-3070, a once-daily asenapine transdermal system, is the first antipsychotic "patch" formulation FDA approved for adults with schizophrenia. Positive and Negative Syndrome Scale (PANSS) score items can be grouped into a five-factor structure to describe specific schizophrenia symptom domains. This post hoc analysis of data from a pivotal study evaluated HP-3070's efficacy by examining these factors.

A systematic review of clozapine for aggression and violence in patients with schizophrenia or schizoaffective disorder.

Although uncommon, the risk of aggression and violence is greater in people with schizophrenia than in the general population. Clozapine is the "gold standard" pharmacologic treatment for the management of persistent agitation and aggression in people with schizophrenia and is consistently recommended by guidelines and reviews for this purpose. Although clozapine is indicated for treatment-resistant schizophrenia based on its superior efficacy, studies have proposed that clozapine may have specific properties that ameliorate aggression and hostility that are distinct from its antipsychotic effects.