PETRICCS Guideline Protocol: A Call to Improve Reporting Standards in Cell Culture Research.

Background: Cell culture studies play an important role in addressing fundamental scientific questions. However, inadequate reporting of these studies results in a lack of transparency and reproducibility. Recognizing the need for improvement, several ongoing efforts, such as CRIS guidelines and the ICLAC checklist, are focused on enhancing best practices for in vitro studies.

Mitrofanoff complications: time-to-event analysis of split versus intact appendix and meta-analysis.

Objectives: To assess the complication rates associated with split versus intact appendix Mitrofanoff procedures using a single-center retrospective analysis and a systematic review with meta-analysis.

Subjects And Methods: The study comprised a retrospective cohort analysis at a single institution, analyzing patients who underwent a laparoscopic-assisted Mitrofanoff with or without splitting the appendix from 2005 to 2016. The focus was on complications related to both Mitrofanoff and ACE channels.

Transient lymphocyte count decrease correlates with oncolytic adenovirus efficacy in humans: mechanistic and biomarker findings from TUNIMO phase I trial.

Background: Oncolytic viruses (OVs) are promising immunotherapeutics to treat immunologically cold tumors. However, research on the mechanism of action of OVs in humans and clinically relevant biomarkers is still sparse. To induce strong T-cell responses against solid tumors, TILT-123 (Ad5/3-E2F-d24-hTNFa-IRES-hIL2, igrelimogene litadenorepvec) was developed.

Self-care conditioning factors in women and men with urinary incontinence and Human T-Lymphotropic Virus Type 1.

Objective: To analyze self-care conditioning factors in women and men with urinary incontinence symptoms living with the Human T-Lymphotropic Virus Type 1.

Method: Qualitative study, based on the pragmatic phase of Praxis Model for Technology Development. Twelve women and five adult men living with Human T-Lymphotropic Virus Type 1, residing in Bahia, Brazil, participated in the study.