Publications by authors named "J B Dekker"

Article Synopsis
  • There is evidence suggesting that using stents or decompressing stomas before surgery for left-sided obstructive colon cancer (LSOCC) is safer than emergency surgery, particularly for patients aged 70 and older.
  • A study analyzing data from 2012 to 2020 showed a decrease in emergency resections, from 79.7% to 54.7%, with an increase in safer approaches like resection after stent or stoma.
  • Despite a national trend towards safer surgical methods, some hospitals still performed over 75% emergency resections, leading to higher mortality rates, emphasizing the need to follow updated guidelines for elderly patients.
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The immunologic consequences of using bactericidal versus bacteriostatic antibiotic treatments are unclear. We observed a bacteriostatic (growth halting) treatment was more protective than a bactericidal (bacteria killing) treatment in a murine peritonitis model. To understand this unexpected difference, we compared macrophage responses to bactericidal treated bacteria or bacteriostatic treated bacteria.

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Article Synopsis
  • This article discusses common questions and symptoms related to STDs that patients frequently raise with general practitioners and special clinics, emphasizing the importance of understanding sexual behavior in making accurate diagnoses.
  • It highlights the need for careful risk assessment and testing policies, particularly for high-risk individuals who should be tested for gonorrhea, syphilis, HIV, and hepatitis B, while also addressing the significance of early detection and treatment.
  • The use of PrEP is mentioned as a preventative measure against HIV, stressing that while it can enhance sexual health, consistent condom usage remains vital for STD prevention.
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Every cell must solve the problem of how to fold its genome. We describe how the folded state of chromosomes is the result of the combined activity of multiple conserved mechanisms. Homotypic affinity-driven interactions lead to spatial partitioning of active and inactive loci.

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Background: Recovery from severe mental illness, including psychosis has been described as a personal and unique process, but it rarely is a journey undertaken without profound influences of significant others (family, mental health professionals). Diverging perspectives between persons with severe mental illness, family and professionals are frequent during the recovery process, notably in psychotic disorders. We aimed to explore processes of collaboration during recovery, to inform recovery supporting practices.

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