Publications by authors named "J B Cara"
Context: In patients with GH deficiency (GHD) receiving GH treatment, IGF-1 concentrations are used by physicians to monitor treatment safety and efficacy and guide dosing decisions. Somatrogon is a long-acting GH approved as a once-weekly treatment for pediatric GHD. Somatrogon administration results in characteristic changes in the IGF-1 profile, with values measured at 96 hours postdose representing mean IGF-1 concentrations that best reflect overall somatrogon exposure.
View Article and Find Full Text PDFThis work aimed to evaluate the use of Visible and Near-infrared Spectroscopy (Vis-NIRS) as a tool in the classification of bovine carcasses. A total of 133 animals (77 females, 29 males surgically castrated and 27 males immunologically castrated) were used. Vis-NIRS spectra were collected in a chilling room 24 h postmortem directly on the hanging carcasses over the longissimus thoracis between the surface of the 5th and 6th ribs.
View Article and Find Full Text PDFComparing the efficacy and safety of weekly somatrogon with daily somatropin to treat children with growth hormone deficiency: a plain language summary of publication.
Ther Adv Endocrinol Metab
November 2024
Article Synopsis
- Weekly injections for treating growth deficiency in children are just as effective as daily injections, showing similar growth rates.
- The safety of weekly injections is comparable to daily injections, indicating no significant risk differences.
- It's important to note that treatment decisions should consider all evidence, not just one study, and approval for the drug may vary by country.
Article Synopsis
- Clavicular brachial plexus blocks, specifically infraclavicular (IC) and supraclavicular (SC) approaches, are used for pain relief in upper limb surgeries, with ongoing debates about which is more effective.
- A review of 18 randomized controlled trials (RCTs) involving 1,389 patients found that IC blocks had a significantly higher success rate than SC blocks, with odds ratio 0.61.
- The study noted variability in how outcomes were reported, recommending future research to standardize definitions for better comparisons.
Development of effective pollution mitigation strategies require an understanding of the pollution sources and factors influencing fecal pollution loading. Fecal contamination of Turkey Creek in Gulfport, Mississippi, one of the nation's most endangered creeks, was studied through a multi-tiered approach. Over a period of approximately two years, four stations across the watershed were analyzed for nutrients, enumeration of E.
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