Publications by authors named "J B Brandt"
Astrocyte regulation of critical period plasticity across neural circuits.
Curr Opin Neurobiol
December 2024
Critical periods are brief windows of heightened neural circuit plasticity that allow circuits to permanently reset their structure and function to facilitate robust organismal behavior. Understanding the cellular and molecular mechanisms that instruct critical period timing is of broad clinical interest, as altered developmental plasticity is linked to multiple neurodevelopmental disorders. While intrinsic, neuronal mechanisms shape both neural circuit remodeling and critical period timing, recent data indicate that signaling from astrocytes and surrounding glia can both promote and limit critical period plasticity.
View Article and Find Full Text PDFClinically Focused Insights on the Placenta and Umbilical Cord: An Evidence-based Symposium.
Clin Obstet Gynecol
December 2024
Article Synopsis
- The symposium presents a series of reviews focused on important clinical aspects of the placenta and umbilical cord, covering conditions like placenta previa and abruption, as well as various pathologies and infections.
- It highlights the critical functions of the umbilical cord as a lifeline for the fetus, discussing how its dysfunction can lead to complications such as vasa previa.
- This collection emphasizes the significance of understanding these structures for ensuring maternal-fetal health throughout pregnancy.
Purpose: To determine the rate of visual field (VF) loss before and after the diagnosis of primary open angle glaucoma (POAG) in the Ocular Hypertension Treatment Study (OHTS).
Design: Prespecified analyses of data collected prospectively in a clinical trial with extended follow-up.
Setting And Participants: Participants who developed POAG during OHTS 1 and 2 (February 1994 to December 2008) constitute an inception cohort.
Article Synopsis
- The study investigates the link between residential greenspace and the impact of COVID-19 on health, focusing on Danish adults 50 and older during the pandemic.* -
- Researchers found that increased greenspace was associated with lower rates of COVID-19 infection, hospitalization, and mortality, especially among vulnerable groups like the elderly and those with chronic illnesses.* -
- Health impact assessments suggested that enhancing local greenspace could have potentially prevented 8-14% of COVID-19 cases in the population studied, indicating benefits of greening initiatives.*
Switchable 3D Photonic Crystals Based on the Insulator-to-Metal Transition in VO.
ACS Appl Mater Interfaces
December 2024
Article Synopsis
- Photonic crystals (PhCs) are optical structures that manipulate light by creating a photonic band gap (PBG) through their dielectric properties, traditionally fixed and static.
- Recent advancements target switchable PhCs, especially using vanadium dioxide (VO), which changes its state and optical properties near room temperature, allowing for a reversible adjustment of the PBG.
- This research introduces a fabrication method for 3D switchable VO photonic crystals, demonstrating significant control over PBG at specific wavelengths in the near-infrared region, paving the way for versatile photonic devices that can adapt their functionalities.