How could 20-minute neighbourhoods impact health and health inequalities? A policy scoping review.

Background: 'Twenty-minute neighbourhoods' (or variations, such as 15-minute cities) are receiving increasing policy attention with anticipated impacts on population health (inequalities) outcomes alongside sustainability improvements. Yet, factors contributing to possible health impacts are not well understood. This scoping review aimed to identify proposed and evidenced pathways to health (inequality) outcomes from international policy plans.

The Impact of Obesity on Postoperative and Perioperative Outcomes in Lumbar Spine Surgery, a Systematic Review and Meta Analysis.

Background Context: Obesity is increasingly prevalent globally and is associated with various health issues, including spine-related disorders. Previous studies have shown mixed results regarding the impact of obesity on spine surgery outcomes.

Purpose: This meta-analysis aims to evaluate the effects of obesity on perioperative and post-operative outcomes in spine surgery patients.

Effect of preventive treatment with atogepant on quality of life, daily functioning, and headache impact across the spectrum of migraine: Findings from three double-blind, randomized, phase 3 trials.

Background: We aimed to assess the effects of preventive migraine treatment with atogepant vs. placebo on patient-reported quality of life and functioning.

Methods: Analyses of patient-reported outcomes from three 12-week, randomized, placebo-controlled trials evaluating preventive migraine treatment with atogepant 60 mg once-daily: ADVANCE (low-frequency episodic migraine [LFEM], 4-8 monthly migraine days [MMDs] and high-frequency episodic migraine [HFEM], 8-14 MMDs), PROGRESS (chronic migraine, CM) and ELEVATE (episodic migraine in those previously failed by two to four classes of oral preventive treatments).

Purpose in life moderates the relationship between perceived discrimination and cognitive functioning in midlife and older adults.

Objectives: Discrimination is associated with worse cognitive outcomes, but research is urgently needed to identify modifiable psychosocial resources that may buffer the impact of discrimination on cognition. Purpose in life is one such resource associated with positive health outcomes. However, it is unclear whether purpose in life may buffer the relationship between discrimination and cognition among older adults.