Uncertainty in Breast Cancer Risk Prediction: A Conformal Prediction Study of Race Stratification.

The use of Artificial Intelligence (AI) in medicine has attracted a great deal of attention in the medical literature, but less is known about how to assess the uncertainty of individual predictions in clinical applications. This paper demonstrates the use of Conformal Prediction (CP) to provide insight on racial stratification of uncertainty quantification for breast cancer risk prediction. The results presented here show that CP methods provide important information about the diminished quality of predictions for individuals of minority racial backgrounds.

Common structural domains in the sarcoplasmic reticulum Ca-ATPase and the transverse tubule Mg-ATPase.

Transverse tubule (TT) membranes isolated from chicken skeletal muscle possess a very active magnesium-stimulated ATPase (Mg-ATPase) activity. The Mg-ATPase has been tentatively identified as a 102-kD concanavalin A (Con A)-binding glycoprotein comprising 80% of the integral membrane protein (Okamoto, V.R.

Individualizing patient care.

Patients are people as well as potential problems. Increasing our awareness of patients' lifestyle preferences, as well as developing more productive ways to interact with them, can promote growth along with recovery. The very least it can do is to facilitate working with patients and reduce the negative impact of stress of conflict in a very demanding profession.

Human autoantibodies against desmosomes: possible causative factors in pemphigus.

Pemphigus is a human disease that causes extensive blistering of the skin. This blistering is related to a loss of epidermal cell cohesion and is accompanied by circulating autoantibodies that stain epidermal cell surfaces, as shown by immunofluorescence microscopy. One of the major components involved in epidermal cell cohesion is the desmosome.