Modification of the synaptic glutamate turnover in the hippocampal tissue exposed to low-frequency, pulsed magnetic fields.

The influence of pulsed magnetic fields (PMF) on the release and uptake of glutamate was investigated. While the release was examined using hippocampal slices, synaptosomes were chosen to characterize the uptake process. (3)H-D-aspartate was used as a marker of glutamergic transmission.

[The effects of the pulsatile administration of naloxone on the secretion of gonadotrophins in a case of hypothalamo-hypophyseal amenorrhea].

12 mg of Naloxone were given using an intravenous pulsatile pump at the rate of 0.4 mg/minute every 8 minutes over a period of 4 hours in a woman of 28 years of age who had secondary amenorrhea of hypothalamic origin. The levels of L.

[Pregnancy provoked by pulsatile administration of gonadotropin- releasing hormone in 2 women with oligomenorrhea].

Pulsatile administration of gonadotropin releasing hormone (GnRH) at a rythm of 1 microgram/min during 6 minutes every 2 hours restored ovulatory cycles and subsequently pregnancy was obtained in 2 patients who presented with oligomenorrhea and sterility.

[Changes in LH, FSH, PRL and estradiol after perfusion with naloxone in normal and amenorrheic women].

Naloxone is antagonistic to endogenous opioids. Giving it shows that these opioids act as controlling mechanisms in the secretion of LH and FSH by the hypothalamic, pituitary system and probably of Gn-RH by the hypothalamus. Endogenous opioids and particularly beta endorphin, which is itself under the control of oestradiol, play an inhibitory role on the secretion of Gn-RH and alter the pulsatile mode of Gn-RH secretion.