[Evaluation of a pilot health promotion and stress management program for Pharmacy and Biochemistry students and professionals].

Objectives: The beneficial results of a theory-practice pilot stress management program for Pharmacy and Biochemistry professionals and students. Its importance as a complement of traditional academic education, as well as its potential for Pharmaceutical Care is also discussed.

Materials And Methods: A total of 27 students and 26 professionals took part in a program of 10 sessions, aimed at improving stress management.

Psychological and physiological response of students to different types of stress management programs.

Purpose: To design, implement, and examine the psychoneuroendocrine responses of three different types of stress management programs.

Design: Randomly assigned. A pre/post experimental design comparing variables between three different programs and a control group.

5-HT4 and 5-HT2 receptors antagonistically influence gap junctional coupling between rat auricular myocytes.

5-hydroxytryptamine-4 (5-HT(4)) receptors have been proposed to contribute to the generation of atrial fibrillation in human atrial myocytes, but it is unclear if these receptors are present in the hearts of small laboratory animals (e.g. rat).

Conformational state of human cardiac 5-HT(4(g)) receptors influences the functional effects of polyclonal anti-5-HT(4) receptor antibodies.

The functional effects of the anti-G21V antibody directed against the second extracellular loop of human heart 5-HT(4) receptors can differ when the receptors are expressed in different cell lines. Here, we extend these studies to show variation in the responses of 5-HT(4(g)) receptors to the antibody within the same expression system. In a previous report no effect of the anti-G21V antibodies had been shown upon 5-HT(4(g)) receptors expressed in CHO cells.

High efficiency activation of L-type Ca2+ current by 5-HT in human atrial myocytes.

In human atrial myocytes, serotonin rather than sympathetic, stimulation is more frequently associated with atrial fibrillation. So does the arrhythmogenic effect of serotonin result from the mechanism of action of the receptor or the context of its action upon cardiac myocytes? The capacity of agonists to produce cAMP followed the sequence 5-HT < Iso < Forskolin to increase ICaL with 5-HT = Iso = Forskolin. The simultaneous application of threshold concentrations of 5-HT and Iso maximally increased ICaL.