Publications by authors named "J Apers"
Purpose: The optimal bowel limb lengths for laparoscopic Roux-en-Y gastric bypass (LRYGB) to maximize weight loss while minimizing nutritional deficiencies in severe obesity treatment remain a topic of debate. The multi-center Dutch Common Channel Trial (DUCATI) aims to compare the outcomes of a very long Roux Limb Roux-en-Y gastric bypass (VLRL-LRYGB) with a standard Roux-en-Y gastric bypass (S-LRYGB).
Methods: A total of 444 patients were randomly assigned in a 1:1, double-blind manner to undergo either VLRL-RYGB or S-LRYGB.
Peroperative administration of tranexamic acid in Roux-en-Y and one-anastomosis gastric bypass to reduce haemorrhage in patients with morbid obesity: protocol for randomised controlled trial (PATRY trial).
BMJ Open
May 2024
Article Synopsis
- The study investigates the effectiveness of tranexamic acid (TXA) in reducing postoperative bleeding in patients undergoing gastric bypass surgery, particularly in the context of Enhanced Recovery After Bariatric Surgery protocols.
- This multicenter, double-blind, randomized controlled trial will involve 1,524 participants across six bariatric centers in the Netherlands, comparing the effects of TXA against a placebo.
- Primary and secondary outcomes will assess hemorrhage rates, surgical details, complications, and costs, with the trial being ethically approved and results planned for publication.
Article Synopsis
- Sleeve gastrectomy is a common weight loss surgery, but its long-term effectiveness compared to Roux-en-Y gastric bypass (RYGB) is unclear, motivating a study to compare their outcomes over five years.
- In a trial involving 628 patients, those receiving RYGB lost more excess BMI (67.1%) compared to sleeve gastrectomy (58.8%), although both procedures showed significant weight loss and improvement in obesity-related health issues.
- Patients who underwent RYGB also experienced greater improvement in certain conditions like dyslipidaemia, while the overall health benefits were notable in both surgical groups after the five years of follow-up.
Background: Laparoscopic incisional hernia repair is increasingly performed worldwide and expected to be superior to conventional open repair regarding hospital stay and quality of life (QoL). The INCisional Hernia-Trial was designed to test this hypothesis.
Methods: A multicenter parallel randomized controlled open-label trial with a superiority design was conducted in six hospitals in the Netherlands.
Introduction: In fast-track metabolic surgery, the window to identify complications is narrow. Postoperative checklists can be useful tools in the decision-making of safe early discharge. The aim of this study was to evaluate the predictive value of a checklist used in metabolic surgery.
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