Publications by authors named "J Anthofer"

Article Synopsis
  • Severe refractory cerebral vasospasm (CV) poses significant risks for patients with aneurysmal subarachnoid hemorrhage (SAH), making effective therapies essential.
  • The study analyzed outcomes from patients treated with different approaches to nimodipine—oral treatment, a single intra-arterial shot, and continuous intra-arterial infusion—highlighting that continuous infusion led to lower rates of cerebral infarction and craniectomy.
  • However, continuous intra-arterial nimodipine was associated with higher rates of VP shunting and tracheotomy, indicating a need for further evaluation of its long-term impact on neurological outcomes and quality of life.
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Tractography based on diffusion-weighted magnetic resonance imaging (DWI) models the structural connectivity of the human brain. Deep brain stimulation (DBS) targeting the subthalamic nucleus is an effective treatment for advanced Parkinson's disease, but may induce adverse effects. This study investigated the relationship between structural connectivity patterns of DBS electrodes and stimulation-induced side effects.

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Objective: Rechargeable neurostimulators for deep brain stimulation have been available since 2008, promising longer battery life and fewer replacement surgeries compared to non-rechargeable systems. Long-term data on how recharging affects movement disorder patients are sparse. This is the first multicenter, patient-focused, industry-independent study on rechargeable neurostimulators.

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Objective: Subthalamic deep brain stimulation may alleviate bradykinesia in Parkinson patients. Research suggests that this stimulation effect may be mediated by brain networks like the corticocerebellar loop. This study investigated the connectivity between stimulation sites and cortical and subcortical structures to identify connections for effective stimulation.

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Deep brain stimulation for Parkinson's disease has become an established treatment option in recent years. The method and its application in clinical practice has proved to be safe and effective. Nevertheless, procedure-related and hardware-related complications occur.

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