Publications by authors named "J Anson"

Article Synopsis
  • * It outlines the authors' experience with a transcranial endovascular approach as a solution for these difficult cases.
  • * The findings suggest that this method is both safe and effective for treating dAVF when other access routes aren't viable.
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Objectives: To report the long-term outcomes from a longitudinal psychosocial study that forms part of the 'Identification of Men with a genetic predisposition to ProstAte Cancer: Targeted Screening in men at higher genetic risk and controls' (IMPACT) study. The IMPACT study is a multi-national study of targeted prostate cancer (PrCa) screening in individuals with a known germline pathogenic variant (GPV) in either the BReast CAncer gene 1 (BRCA1) or the BReast CAncer gene 2 (BRCA2).

Subjects And Methods: Participants enrolled in the IMPACT study were invited to complete a psychosocial questionnaire prior to each annual screening visit for a minimum of 5 years.

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An unusual case of ischemic stroke due to calcified cerebral embolus occurring in a pregnant patient during the peripartum period is reported. The source of the embolus was suspected to be a pelvic phlebolith in origin which paradoxically embolized via a patent foramen ovale to the supraclinoid right internal carotid artery. To our knowledge, this is the first reported case of calcified cerebral embolus attributed to paradoxical embolism of a pelvic phlebolith, and we theorize that introduction of the phlebolith into the venous system may have occurred as a consequence of vascular remodeling due to pregnancy-related hemodynamic changes.

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Drug treatment courts (DTC) address substance use disorders (SUD) but not cooccurrencing HIV or hepatitis C virus (HCV). This pilot explored feasibility and preliminary outcomes of the Women's Initiative Supporting Health (WISH) intervention and health-related motivation, both based in self-determination theory (SDT) regarding HIV/HCV and SUD treatment. WISH feasibility study: 79 DTC women completed a one-time survey regarding motivation and willingness to engage in future interventions.

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Article Synopsis
  • Li-Fraumeni syndrome (LFS) is a hereditary condition linked to a higher risk of various cancers, with about 70% of affected individuals carrying a detectable genetic variant, but some still remain cancer-free.
  • Researchers analyzed the genomes of 396 LFS patients to uncover additional cancer-related genetic factors and identified alternative cancer-associated mutations in those without a known variant.
  • The study highlights the need for more comprehensive genetic testing in LFS patients and suggests that cancer risk cannot be solely attributed to single gene mutations, but rather involves a complex interplay of genetic and epigenetic factors.
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