Publications by authors named "J Anne Kynaston"

Objective: Despite the high prevalence and significant implications of pediatric hydrocephalus, the etiological distribution of pediatric hydrocephalus across the diverse Asian demographic is poorly understood. This study aimed to inform clinical guidelines and public health decisions by identifying the etiological distribution of pediatric hydrocephalus across Asia.

Methods: In this systematic review and meta-analysis, the authors searched EMBASE, MEDLINE, CENTRAL, Global Health, Global Index Medicus, and Scopus, with no language restriction, from inception to January 27, 2023.

View Article and Find Full Text PDF

Background: Some 28% of the Scottish population suffer from obesity. Bariatric procedures per population carried out in England when compared to Scotland (NBSR 2018) are significantly higher. Primary care practitioners (PCP) influence equality of access to secondary care bariatrics and frequently manage post-operative bariatric patients.

View Article and Find Full Text PDF

We develop theoretical equivalences between stochastic and deterministic models for populations of individual cells stratified by age. Specifically, we develop a hierarchical system of equations describing the full dynamics of an age-structured multistage Markov process for approximating cell cycle time distributions. We further demonstrate that the resulting mean behavior is equivalent, over large timescales, to the classical McKendrick-von Foerster integropartial differential equation.

View Article and Find Full Text PDF

Aim: Human parechovirus (HPeV) is an increasingly recognised cause of severe illness and central nervous system infection in infants. Medium- to long-term neurodevelopmental outcomes post-HPeV infection remain unknown. This study aims to assess neurodevelopmental outcomes for children hospitalised as infants with HPeV infection in their second and third years of life.

View Article and Find Full Text PDF
Article Synopsis
  • A study analyzed hospitalized pertussis cases in Australia from 2012 to 2019, focusing on the effects of antenatal vaccination on severe pertussis cases in children aged 0 to 15 years.
  • Results showed a significant decrease in cases under 2 months of age after the introduction of maternal vaccination, with vaccine effectiveness estimated at 84.3%.
  • Despite high immunization rates, older children (12+ months) still accounted for a notable percentage of hospitalizations, highlighting the need for new vaccine strategies to further protect this age group.
View Article and Find Full Text PDF