Cohort mortality study of employees at the Celanese plant in Pampa, Texas.

Background: The mortality experience of chemical workers from the Pampa, Texas Celanese Ltd. plant through 1991 has been previously reported. This study updates that effort and presents an additional seven years of data and follow-up that provided 268 additional cohort members and 71 new deaths.

An historical cohort mortality study of synthetic fiber workers potentially exposed to glycerol polyglycidyl ether.

We report an update of the mortality experience of a cohort of 8878 employees who worked between November 1, 1965, and December 31, 1988, at a synthetic fiber manufacturing facility with potential exposure to glycerol polyglycidyl ether (T55) and were followed through December 31, 1998. The mortality experience of the race/gender groups within the cohort was strikingly similar, with both the all causes of death and all cancer causes of death below unity on both national and local standards. For white men, there were no statistically significant increases for any cause of death, with the exception of benign neoplasms.

Observed versus predicted carboxyhemoglobin levels in cellulose triacetate workers exposed to methylene chloride.

Background: Occupational exposure to methylene chloride, together with carboxyhemoglobin concentrations, has not been studied previously.

Methods: Carboxyhemoglobin levels were measured in non-smoking employees exposed to varying concentrations of methylene chloride during the manufacture of cellulose triacetate fibers. The observed carboxyhemoglobin levels were compared to predicted concentrations using a pharmacokinetic model.

Cohort mortality study of prostate cancer among chemical workers.

A retrospective cohort mortality study was conducted at a chemical plant producing acetic acid and acetic anhydride, two chemicals essential in the synthesis of cellulose triacetate fiber. Previously, we reported excess mortality from biliary tract and prostate cancers among workers in cellulose triacetate fiber manufacturing plants. In the present investigation, an excess of prostate cancer (SMR = 330.

A cohort mortality study of cellulose triacetate-fiber workers exposed to methylene chloride.

The purpose of this study of 3211 cellulose-fiber production workers was to evaluate earlier findings of excess biliary tract and liver cancer in a similarly exposed cohort reported in 1990. Mortality from biliary tract and liver cancer was not increased in this study population, and there was no excess mortality from pancreatic cancer. Mortality was not elevated for cancers of the lung or liver, sites at which tumors were induced in experimental animals exposed to methylene chloride.