Global expansion of human-wildlife overlap in the 21st century.

Understanding the extent to which people and wildlife overlap in space and time is critical for the conservation of biodiversity and ecological services. Yet, how global change will reshape the future of human-wildlife overlap has not been assessed. We show that the potential spatial overlap of global human populations and 22,374 terrestrial vertebrate species will increase across ~56.

Electronic data capture in resource-limited settings using the lightweight clinical data acquisition and recording system.

Our prototype system designed for clinical data acquisition and recording of studies is a novel electronic data capture (EDC) software for simple and lightweight data capture in clinical research. Existing software tools are either costly or suffer from very limited features. To overcome these shortcomings, we designed an EDC software together with a mobile client.

Peripheral priming induces plastic transcriptomic and proteomic responses in circulating neutrophils required for pathogen containment.

Neutrophils rapidly respond to inflammation and infection, but to which degree their functional trajectories after mobilization from the bone marrow are shaped within the circulation remains vague. Experimental limitations have so far hampered neutrophil research in human disease. Here, using innovative fixation and single-cell-based toolsets, we profile human and murine neutrophil transcriptomes and proteomes during steady state and bacterial infection.