Publications by authors named "J Alfonso Masa"
Introduction: Understanding the diverse pathogenetic pathways in obstructive sleep apnea (OSA) is crucial for improving outcomes. microRNA (miRNA) profiling is a promising strategy for elucidating these mechanisms.
Objective: To characterize the pathogenetic pathways linked to OSA through the integration of miRNA profiles, machine learning (ML) and bioinformatics.
Article Synopsis
- Obstructive sleep apnea (OSA) significantly impacts cardiovascular event recurrence in patients with acute coronary syndrome (ACS), particularly in those without prior cardiovascular disease.
- The study identified two groups based on the severity of OSA and utilized proteomics to analyze plasma proteins, revealing 24 differentially expressed proteins associated with OSA severity.
- Bioinformatic analysis suggested that these proteins are involved in key molecular pathways related to immune function, cell signaling, and inflammation, linking OSA to adverse cardiovascular outcomes.
Introduction: Among all patients with hypertension, those with resistant hypertension (RH) have the highest rates of subclinical organ damage (SOD). The prevalence of obstructive sleep apnea (OSA) is high in RH patients, and it could contribute to SOD. We aimed to investigate how OSA and its treatment are related to SOD in a large cohort of RH patients.
View Article and Find Full Text PDFBackground: There is a close relationship between obstructive sleep apnoea (OSA) and resistant hypertension (RH). However, studies assessing the long-term effect of diagnosing and treating OSA on blood pressure (BP) control in these patients are lacking.
Methods: To address this gap, we recruited 478 RH patients from hypertension units and followed them prospectively after they were screened for OSA through a sleep study.
Ni-Xides (B, S, and P) for Alkaline OER: Shedding Light on Reconstruction Processes and Interplay with Incidental Fe Impurities as Synergistic Activity Drivers.
ACS Appl Energy Mater
February 2024
Article Synopsis
- * Research focused on comparing the oxygen evolution reaction (OER) of NiB, NiP, and NiS in both purified (P-KOH) and unpurified (Un-KOH) potassium hydroxide solutions using various analytical techniques and found that Fe impurities play a significant role in enhancing OER activity.
- * The study revealed that while there was no notable performance difference among the Ni-Xides in P-KOH, OER activity was notably higher in Un