Publications by authors named "J Alexander Willemse"
Objective: This study evaluates the effectiveness of calcium supplementation as a preventive measure for pregnant women with insufficient calcium intake, examining adherence to the recommended 1000 mg daily intake and identifying influencing factors.
Methods: A survey (Expect cohort II, n = 823) evaluated calcium adherence among pregnant women, followed by interviews with sixteen purposefully selected participants. Verbatim transcripts were independently analyzed to identify key themes.
Background: Achieving competence in clinical skills requires various resources and preparation time for undergraduate nursing students. Intentional opportunities should be created for student nurses to experience meaningful encounters in the clinical skills laboratory (CSL) to broaden their knowledge and competence. Therefore, factors that influence the competence in clinical learning in a CSL were explored.
View Article and Find Full Text PDFPurpose: This study aimed to evaluate the added benefit of body MRI (covering the chest, abdomen, and pelvis) to detect the primary tumour in patients with adenocarcinoma of unknown primary (ACUP) and a suspected abdominal malignancy in whom previous diagnostic work-up with CT and/or FDG-PET/CT did not yield a primary tumour diagnosis.
Methods: Thirty ACUP patients with a suspected primary tumour in the abdomen/pelvis (based on pathology and/or pattern of disease) underwent MRI (T2-weighted, DWI, pre- and post-contrast T1-weighted) after completion of their initial diagnostic work-up with CT and/or PET/CT. Effects of MRI to establish a primary tumour diagnosis (and to detect additional metastatic sites) were documented.
Article Synopsis
- - Osteogenesis imperfecta (OI) is a genetic disorder affecting collagen type I, leading to fragile bones and a heightened risk of eye diseases due to collagen's role in various eye tissues.
- - The sclera, which contains a significant amount of collagen type I, is crucial for eye structure and has a unique fiber arrangement that may provide support to the optic nerve; however, the effects of abnormal collagen on this tissue are not fully understood.
- - This study used polarization-sensitive optical coherence tomography (PS-OCT) to analyze collagen fiber orientation in the sclera near the optic nerve in individuals with OI compared to healthy individuals, showing that the orientation patterns were similar between the two groups.