Publications by authors named "J Alberto Molina"
Article Synopsis
- Autologous Stem-Cell Transplantation (ASTC) is effective for treating certain blood cancers but can cause severe side effects due to intense chemotherapy.
- The study presents a protocol for performing ASTC without transfusions, catering to patients who decline blood products, such as Jehovah's Witnesses (JW).
- In a small trial with four patients (two with multiple myeloma and two with lymphomas), no serious complications occurred, and all patients remained alive and well at the time of reporting, showcasing the viability of the transfusion-free approach.
Pancreatic cancer in people with HIV: a case-control study.
J Acquir Immune Defic Syndr
December 2024
Background: We aimed to estimate the incidence and to assess the risks factors associated with pancreatic cancer (PC) in people with HIV (PWH).
Setting: We used electronic medical record data from 2009 to 2020 available in the COREVIH Ile-de-France Est database of PWH treated in Paris' public hospitals.
Methods: We analyzed data on patient demographics, treatment history, and immuno-virologic status.
The Janus kinase 2 (JAK2) V617F mutation activates the transcription pathway and has been well-characterized as a driver of myeloproliferative neoplasms (MPNs). Recently, there has been a heightened interest in understanding germline predisposition to hematological malignancies including MPN, including several reports of familial MPN. Here, we retrospectively analyzed medical records and data from genetic testing to describe twelve patients with germline variants at amino acid position 564 of JAK2.
View Article and Find Full Text PDFMolina JC, Rotz S. Acute lymphoblastic leukemia in young adults: which up-front treatment? Hematology Am Soc Hematol Educ Program. 2023;2023(1):573-580.
Hematology Am Soc Hematol Educ Program
December 2024