Publications by authors named "J Adam Leigh"

Health-related behavioral changes may occur following traumatic brain injury. We focused on understanding the impact of mild traumatic brain injury (TBI) on health-related behaviors and identifying factors associated with such changes. We utilized health check-up records from the Korean National Health Insurance Service database spanning January 1, 2009, to December 31, 2017.

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Background: Frozen road conditions could be a factor in road traffic injuries, and seasonality and urbanisation level are potential influencing factors. However, few studies have considered this relationship. Therefore, we examined the effect of frozen road conditions on road traffic injury rates and the differences across seasons and urbanisation levels.

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Background: Ki-67's response to pre-operative endocrine therapy (ET) in early breast cancer is an evidence-based tool to guide adjuvant treatment decisions. Physicians across Canada were surveyed to explore current practice patterns and perceived barriers to the use of Ki-67 in practice.

Methods: Physicians were invited to participate in an anonymous survey and were eligible if they prescribed systemic therapy for breast cancer in Canada.

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Background And Objective: The composition of gut microbiota plays an important role in predicting and influencing outcomes of cancer treated with immunotherapy. Our objective is to summarize the role of gut microbiota and immunotherapy in breast cancer.

Methods: A systematic search from inception until July 2024 of key search terms including immunity, breast neoplasm, gastrointestinal microbiome/microbiota, fecal microbiota transplantation, pro- and prebiotics, antibiotics and immunotherapy using EMBASE, MEDLINE and CENTRAL was conducted.

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