Publications by authors named "J A van Dalen"

Article Synopsis
  • This study evaluates the effectiveness of different sunitinib dosing regimens in treating metastatic renal cell carcinoma in Sweden from 2006 to 2019.
  • The analysis shows significant differences in both time-to-treatment discontinuation and overall survival among the dosing regimens, with the 2-weeks on, 1-week off schedule showing the best outcomes.
  • Despite these findings suggesting that alternative dosing could enhance treatment efficacy, careful interpretation is necessary due to changing treatment patterns and lack of patient risk category data.
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Background: Current prediction models for mainland Europe do not include ethnicity, despite ethnic disparities in cardiovascular disease (CVD) risk. SCORE2 performance was evaluated across the largest ethnic groups in the Netherlands and ethnic backgrounds were added to the model.

Methods: 11,614 participants, aged between 40 and 70 years without CVD, from the population-based multi-ethnic HELIUS study were included.

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Background: The anterior femoral cortical window is an attractive alternative to the extended trochanteric osteotomy when removing femoral cement in revision hip arthroplasty. CT-based additive manufacturing technology has now permitted the creation of patient-specific instrumented (PSI) jigs to facilitate this. The jig simplifies creation of the window, potentiating medullary exposure through an optimally-sized window and therefore cement removal.

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