Left atrial appendage occlusion in patients with atrial fibrillation and intracerebral haemorrhage associated with cerebral amyloid angiopathy: a multicentre observational study and pooled analysis of published studies.

Background: Cerebral amyloid angiopathy (CAA) is a common cause of intracerebral haemorrhage (ICH) with a high recurrence risk. Left atrial appendage occlusion (LAAO) is a method for ischaemic stroke prevention in patients with atrial fibrillation (AF), potentially reducing the risk of intracranial bleeding in CAA-associated ICH. We aimed to determine the outcomes of patients with AF with CAA-associated ICH undergoing LAAO.

Bridging the gap: building and sustaining recovery capital in the transition from prison to recovery residences.

The transition from jail to community is a high-risk time for individuals experiencing substance use disorders (SUD), with elevated risks of overdose and other substance-related harms, as well as high recidivism rates and re-incarceration. Gains made from successful treatment in prison are often lost in this transition. The current paper evaluates this process for one justice programme, Chesterfield HARP, a Therapeutic Community based in the Chesterfield County jail that continues supporting former inmates through their release by examining engagement and retention rates and changes in recovery capital among incarcerated individuals before incarceration and after transition to recovery housing in the community.

The Challenges and Lessons Learned Building a New UK Infrastructure for Finding and Accessing Population-Wide COVID-19 Data for Research and Public Health Analysis: The CO-CONNECT Project.

The COVID-19-Curated and Open Analysis and Research Platform (CO-CONNECT) project worked with 22 organizations across the United Kingdom to build a federated platform, enabling researchers to instantaneously and dynamically query federated datasets to find relevant data for their study. Finding relevant data takes time and effort, reducing the efficiency of research. Although data controllers could understand the value of such a system, there were significant challenges and delays in setting up the platform in response to COVID-19.

Resilience throughout and beyond COVID-19: a longitudinal analysis.

Defined as the ability to adapt to adversity with a positive and stable mindset, resilience should be an important factor in coping with long-term evolving setbacks such as the COVID-19 pandemic. Although the negative mental health impacts of the pandemic are well-documented, the course of resilience during the pandemic and recovery periods remains understudied. This study examined resilience trajectories among respondents in the Canadian Personal Impacts of COVID-19 Survey (PICS) who provided data for at least two timepoints ( = 741).

Snip, Support, and Shared Stories: Exploring Reddit Users' Experiences With Vasectomy.

Introduction Vasectomy is a common procedure for male sterilization. During pre-procedural counseling, men and their partners are often concerned with postoperative pain or sexual dysfunction. Research examining internet forums to explore these concerns is limited.