Emerging cancer therapies: targeting physiological networks and cellular bioelectrical differences with non-thermal systemic electromagnetic fields in the human body - a comprehensive review.

A steadily increasing number of publications support the concept of physiological networks, and how cellular bioelectrical properties drive cell proliferation and cell synchronization. All cells, especially cancer cells, are known to possess characteristic electrical properties critical for physiological behavior, with major differences between normal and cancer cell counterparts. This opportunity can be explored as a novel treatment modality in Oncology.

Erratum: First Search for Dyons with the Full MoEDAL Trapping Detector in 13 TeV pp Collisions [Phys. Rev. Lett. 126, 071801 (2021)].

This corrects the article DOI: 10.1103/PhysRevLett.126.

Non-Equilibrium Quantum Brain Dynamics: Water Coupled with Phonons and Photons.

We investigate Quantum Electrodynamics (QED) of water coupled with sound and light, namely Quantum Brain Dynamics (QBD) of water, phonons and photons. We provide phonon degrees of freedom as additional quanta in the framework of QBD in this paper. We begin with the Lagrangian density QED with non-relativistic charged bosons, photons and phonons, and derive time-evolution equations of coherent fields and Kadanoff-Baym (KB) equations for incoherent particles.

The synergy between alkylating agents and ERCC1-XPF inhibitors is p53 dependent.

Background: DNA repair plays a major role in maintaining genomic stability, thus limiting the transformation of normal cells into cancer cells. However, in cancer patients treated with DNA-targeting drugs, DNA repair can decrease efficacy by removing the damage generated by such molecules that is needed to induce pharmacological activity. Inhibiting DNA repair thus represents an interesting approach to potentiating the activity of chemotherapy in this setting.

The Generation of ROS by Exposure to Trihalomethanes Promotes the IκBα/NF-κB/p65 Complex Dissociation in Human Lung Fibroblast.

Disinfection by-products used to obtain drinking water, including halomethanes (HMs) such as CHCl, CHCl, and BrCHCl, induce cytotoxicity and hyperproliferation in human lung fibroblasts (MRC-5). Enzymes such as superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GPx) modulate these damages through their biotransformation processes, potentially generating toxic metabolites. However, the role of the oxidative stress response in cellular hyperproliferation, modulated by nuclear factor-kappa B (NF-κB), remains unclear.