Publications by authors named "J A Thornhill"
Age-related loss of muscle mass and strength is a highly prevalent condition in older adults in long-term care (LTC) facilities. This pilot study aimed to test the effects of a vitality acupunch (VA) exercise program on muscle mass, muscle strength, muscle endurance, functional fitness, activities of daily living, quality of life, and sleep quality of older adults in LTC facilities with probable sarcopenia in the United States and understand the experiences of residents who participated in the VA program. A mixed-methods experimental design was used for this study.
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- This research explores whether structured clinical data can predict dementia diagnoses, using a machine learning model on a population-based cohort.
- The study linked healthcare data and sociodemographic information, finding that 12.4% of participants were diagnosed with dementia, with Random Forest models yielding an Area Under the Curve (AUC) of 0.67 for overall predictions.
- While structured clinical data showed some predictive capability, using ICD codes improved accuracy to 0.77, indicating a need for further research to ensure these models accurately identify true dementia cases.
Article Synopsis
- The COVID-19 pandemic led to a significant increase in virtual healthcare services, prompting a review of how effective these methods are for delivering HIV care, particularly for marginalized groups.
- A systematic review analyzed data from 4143 records, ultimately including 26 studies that primarily used videoconferencing for consultations between healthcare workers and people living with HIV (PLHIV).
- Results showed that virtual care (VC) is generally accepted by PLHIV, with high attendance and satisfaction rates, and it effectively supports virological outcomes, highlighting the need for diverse care models and proper training for successful implementation.
This study aims to understand the impact of early antiretroviral therapy (ART) on HIV-specific T-cell responses measured after treatment interruption, which may inform strategies to deliver ART-free immune-mediated viral suppression. HIV-specific T-cell immunity was analysed using gamma interferon enzyme-linked immunospot assays in two studies. SPARTAC included individuals with primary HIV infection randomised to 48 weeks of ART (n = 24) or no immediate therapy (n = 37).
View Article and Find Full Text PDFIntroduction: Clinical notes, biomarkers, and neuroimaging have been proven valuable in dementia prediction models. Whether commonly available structured clinical data can predict dementia is an emerging area of research. We aimed to predict Alzheimer's disease (AD) and Alzheimer's disease related dementias (ADRD) in a well-phenotyped, population-based cohort using a machine learning approach.
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