Sulfur-linked cyanoterphenyl-based liquid crystal dimers and the twist-bend nematic phase.

The synthesis and characterisation of two series of cyanoterphenyl-based liquid crystal dimers containing sulfur links between the spacer and mesogenic units, the 3-{ω-[(4'-cyano-[1,1'-biphenyl]-4-yl)thio]alkyl}-[1,2:2,3-terphenyl]-1-carbonitriles (CBSCT), and the 3-({ω-[(4'-cyano-[1,1'-biphenyl]-4-yl)thio]alkyl}oxy)-[1,2:2,3-terphenyl]-1-carbonitriles (CBSOCT) are described. The odd members of both series show twist-bend nematic and nematic phases, whereas the even members exhibit only the nematic phase. This is consistent with the widely held view that molecular curvature is a prerequisite for the observation of the twist-bend nematic phase.

Twist-bend liquid crystal phases and molecular structure: the role of methoxybiphenyl.

The synthesis and characterisation of the 4-[{[4-({6-[4-(4-methoxyphenyl)phenyl]hexyl}oxy)phenyl]methylidene}amino]phenyl 4-alkyloxybenzoates is reported. These are referred to using the acronym MeOB6OIBeO in which denotes the number of carbon atoms in the terminal alkyloxy chain and is varied from one to ten. All ten members exhibit an enantiotropic conventional nematic (N) phase.

Leadless Pacemaker vs. Transvenous Pacemaker in End Stage Kidney Disease: Insights from the Nationwide Readmission Database.

: Leadless pacemakers offer a safe and effective alternative pacing strategy. However, limited data are available for patients with end stage renal disease (ESRD), a population of significant relevance. Using the Nationwide Readmission Database, we extracted data from all adult patients with ESRD who underwent traditional transvenous or leadless pacemaker implantation between 2016 and 2021.

Coancestry superposed on admixed populations yields measures of relatedness at individual-level resolution.

The admixture model is widely applied to estimate and interpret population structure among individuals. Here we consider a "standard admixture" model that assumes the admixed populations are unrelated and also a generalized model, where the admixed populations themselves are related via coancestry (or covariance) of allele frequencies. The generalized model yields a potentially more realistic and substantially more flexible model that we call "super admixture".

Lessons Learned From the Use of Human-Centered Design Approaches to Improve Nutrition in Nigeria.

Improving children's diets from 6 to 24 months can support children's survival, growth, and development, but progress toward this goal has stalled globally. Human-centered design offers a new approach to resolving program challenges, especially when integrated with social and behavior change (SBC) theory and rigorous evaluation. Two human-centered design processes were conducted.