Objectives: To assess glycerol as reference material for low-resolution time-domain (1)H NMR analysis of fecal fat.
Design And Methods: NMR analysis of fecal fat in stool samples with added glycerol was used to assess linearity, recovery, and relationship with NMR lipid signal.
Results: The study revealed for added glycerol excellent linearity (r=0.
Flavopiridol is a novel semisynthetic flavone derivative of the alkaloid rohitukine. Flavopiridol is known to inhibit potently the activity of multiple cyclin-dependent kinases. We have assessed its effects on normal and malignant cells in preclinical animal models of localized and disseminated human hematopoietic neoplasms.
View Article and Find Full Text PDFThe prevalence and severity of adventitious bursitis and its association with age at slaughter and carcase quality were evaluated in a cohort of 1011 pigs reared in a straw-based system. The prevalence of bursitis was 85.4 per cent (574/672).
View Article and Find Full Text PDFWe have investigated human lactate dehydrogenase (LDH) isoenzymes and human nuclear matrix protein 41/7 (NMP 41/7) as potential serologic markers to monitor the course of human leukemia in severe combined immunodeficient (SCID) mice. Following the transplantation of 10(6) human acute lymphoblastic leukemia (ALL) Nalm-6 cells, human specific LDH isoenzymes were measurable in the serum of SCID mice as early as 7 days after transplantation, although serum total LDH increased in some animals as early as 5 days after transplantation. Human NMP 41/7 was measurable in all animals at day 15 after leukemia cell injection.
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