Publications by authors named "J A Stefan"

Article Synopsis
  • - The study focuses on mapping and analyzing areas vulnerable to malaria in Northern Plateau State, Nigeria, as a crucial step for planning interventions and managing resources effectively against malaria infections.
  • - Using environmental risk factors, researchers identified high-risk areas covering over 4,000 km², with 60% of the region exhibiting a significant risk of malaria transmission, particularly near certain local government areas.
  • - The resulting malaria risk map demonstrated high predictive accuracy and sensitivity, providing policymakers with valuable insights for targeted malaria control measures and better understanding of the disease's dynamics.
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  • - The study aimed to evaluate anxiety, depression, and quality of life (QoL) among individuals with type 1 (T1D) and type 2 diabetes (T2D) compared to matched controls during the COVID-19 pandemic's second wave.
  • - Researchers collected data from 203 T1D and 413 T2D individuals, along with 282 controls, through questionnaires on mental health, QoL, and blood samples to assess coronavirus antibody levels.
  • - Findings indicated that younger individuals and health issues were linked to higher anxiety and depression, with T1D showing a greater SARS-CoV-2 NCP infection rate, potentially due to factors like age and employment status.
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Article Synopsis
  • SARS-CoV-2, the virus responsible for COVID-19, produces various subgenomic RNAs (sgRNAs) that play roles in viral gene expression, though their functions are not entirely understood.
  • Host agents like insulin and interferon-gamma, along with the virus's spike protein, enhance the expression of these sgRNAs by promoting the binding of a specific host protein complex to the viral RNA's 3'-end.
  • A newly identified RNA element (SPEAR) in the virus's 3'-end increases sgRNA activity and viral translation, presenting a potential therapeutic target to reduce SARS-CoV-2 levels effectively.
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Importance: The Patient Protection and Affordable Care Act (ACA) individual marketplaces are a source of insurance for millions of residents in the US. However, the association between enrollee risk, health spending, and metal tier selection remains unclear.

Objectives: To describe individual marketplace enrollees' metal tier selections by risk score and assess enrollees' health spending by metal tier, risk score, and spending type.

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PURPOSE OF THE STUDY In the last number of years, the anatomic hemiarthoplasty has gradually been pushed out of clinical practice by modern reverse shoulder arthroplasty (RSA) designs. This is due to the clear excellent functional results of RSAs in a wide spectrum of indication criteria. Nevertheless, RSAs have several possible complications that cannot occur in an anatomic hemiarthroplasty.

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