Publications by authors named "J A Spertus"
Background: The relationship between the extent and severity of stress-induced ischemia and the extent and severity of anatomic coronary artery disease (CAD) in patients with obstructive CAD is multifactorial and includes the intensity of stress achieved, type of testing used, presence and extent of prior infarction, collateral blood flow, plaque characteristics, microvascular disease, coronary vasomotor tone, and genetic factors. Among chronic coronary disease participants with site-determined moderate or severe ischemia, we investigated associations between ischemia severity on stress testing and the extent of CAD on coronary computed tomography angiography.
Methods: Clinically indicated stress testing included nuclear imaging, echocardiography, cardiac magnetic resonance imaging, or nonimaging exercise tolerance test.
Article Synopsis
- A study examined patients with acute myocardial infarction (AMI) who lack standard modifiable risk factors (SMuRFs) to see how it affects their health status over time.
- Out of 4,076 patients studied, those without SMuRFs showed initially better health status scores but their long-term improvements were similar to those with SMuRFs.
- Findings suggest that AMI patients without SMuRFs can achieve comparable health status after 12 months, indicating less need for aggressive secondary prevention measures.
Importance: Sodium-glucose cotransporter-2 inhibitors (SGLT2is) are the first therapy shown to improve clinical outcomes for patients with heart failure (HF) and a left ventricular ejection fraction (LVEF) greater than 40%. Nationwide adoption of SGLT2is in the US since publication of the Empagliflozin Outcome Trial in Patients With Chronic Heart Failure With Preserved Ejection Fraction (EMPEROR-Preserved) in August 2021 is unknown.
Objective: To examine trends and hospital-level variation in SGLT2i adoption.