Publications by authors named "J A Simoneau"

Tissue-agnostic, molecularly targeted therapies are becoming increasingly common in cancer treatment. The molecular drivers of some classes and subclasses of tumors are rapidly being uncovered in an era of deep tumor sequencing occurring at the time of diagnosis. When and how targeted therapies should fit within up-front cytotoxic chemotherapy and radiation paradigms is yet to be determined, because many of them have been studied in single-arm studies in patients with relapsed or refractory cancer.

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  • Premature infants with bronchopulmonary dysplasia (BPD) are at risk for pulmonary hypertension (PH), and this study explores the connection between patent ductus arteriosus (PDA) management strategies and the prevalence of BPD-PH.
  • The research involved examining newborns under 29 weeks gestational age with BPD across two centers—one with a conservative PDA approach and the other with a more aggressive treatment method.
  • Findings indicated similar rates of PH between the two centers despite different PDA treatment rates, suggesting that a conservative approach does not increase the likelihood of PH diagnosis in these infants.
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The Gottesman-Kitaev-Preskill (GKP) code encodes a logical qubit into a bosonic system with resilience against single-photon loss, the predominant error in most bosonic systems. Here we present experimental results demonstrating quantum error correction of GKP states based on reservoir engineering of a superconducting device. Error correction is made fully autonomous through an unconditional reset of an auxiliary transmon qubit.

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  • A study was conducted to explore how the severity of congenital diaphragmatic hernia (CDH) affects patients' perceptions of their quality of life (QOL).
  • Researchers used the Pediatric Quality of Life Inventory (PedsQL) to gather data from patients aged 5 and older and found that those with severe CDH reported significantly lower QOL scores, especially in areas like physical activity and social interactions.
  • The findings highlight the need for better health monitoring and improvements in care based on patient experiences, particularly for those with severe cases of CDH.
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