Publications by authors named "J A Sidler"

Aims Of The Study: We aimed to assess a potential association of iron status with mortality and morbidity of inpatients with systemic inflammation.

Methods: This was a single centre prospective observational study. From April 2014 to October 2014, all consecutive medical inpatients aged >=18 years with a C-reactive protein value >5 mg/l on hospital admission were eligible for the study.

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Article Synopsis
  • The study investigates the impact of low-dose acetylsalicylic acid (aspirin) on mortality rates in patients with Staphylococcus aureus bloodstream infections compared to those with Escherichia coli infections.
  • A cohort of 838 S. aureus and 602 E. coli infection episodes was analyzed, revealing that 12.1% of patients with S. aureus who took acetylsalicylic acid died within 30 days, compared to 27.4% of those who did not, suggesting a significant reduction in mortality.
  • In contrast, there was no significant mortality benefit observed in patients with E. coli infections taking acetylsalicylic acid, indicating a targeted effect for S. aureus
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Screening for Pseudomonas aeruginosa is recommended to guide empirical antimicrobial therapy in patients on high-risk units. However, evidence for this approach is scarce. We therefore screened 1310 patients with severe haematologic diseases for P.

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Objective: Little is known about optimal management of prosthetic vascular graft infections, which are a rare but serious complication associated with graft implants. The goal of this study was to compare and characterize these infections with respect to the location of the graft and to identify factors associated with outcome.

Methods: This was a retrospective study over more than a decade at a tertiary care university hospital that has an established multidisciplinary approach to treating graft infections.

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