alkyl quinolone response is dampened by .

Unlabelled: The bacterium is an opportunistic pathogen that can cause lung, skin, wound, joint, urinary tract, and eye infections. While is known to exhibit a robust competitive response toward other bacterial species, this bacterium is frequently identified in polymicrobial infections where multiple species survive. For example, in prosthetic joint infections, can be identified along with other pathogenic bacteria including , , and .

Alkyl Quinolone Response is dampened by .

The bacterium is an opportunistic pathogen that can cause lung, skin, wound, joint, urinary tract, and eye infections. While is known to exhibit a robust competitive response towards other bacterial species, this bacterium is frequently identified in polymicrobial infections where multiple species survive. For example, in prosthetic joint infections (PJIs), can be identified along with other pathogenic bacteria including and Here we have explored the survival and behavior of such microbes and find that readily survives culturing with while other tested species do not.

Alkyl quinolones mediate heterogeneous colony biofilm architecture that improves community-level survival.

Bacterial communities exhibit complex self-organization that contributes to their survival. To better understand the molecules that contribute to transforming a small number of cells into a heterogeneous surface biofilm community, we studied acellular aggregates, structures seen by light microscopy in colony biofilms using light microscopy and chemical imaging. These structures differ from cellular aggregates, cohesive clusters of cells important for biofilm formation, in that they are visually distinct from cells using light microscopy and are reliant on metabolites for assembly.

Metabolic insights from mass spectrometry imaging of biofilms: A perspective from model microorganisms.

Biofilms are dense aggregates of bacterial colonies embedded inside a self-produced polymeric matrix. Biofilms have received increasing attention in medical, industrial, and environmental settings due to their enhanced survival. Their characterization using microscopy techniques has revealed the presence of structural and cellular heterogeneity in many bacterial systems.

Metabolic and Oxidative Stress Effects on the Spectroelectrochemical Behavior of Single Cells.

is an opportunistic human pathogen capable of causing a wide range of diseases in immunocompromised patients. In order to better understand behavior and virulence and to advance drug therapies to combat infection, it would be beneficial to understand how cells survive stressful conditions, especially environmental stressors. Here, we report on a strategy that measures potential-dependent fluorescence of individual cells, as a sentinel, for cellular response to starvation, hunger, and oxidative stress.