Publications by authors named "J A Sargeant"
Article Synopsis
- Weight loss can inadvertently lead to a decrease in both lean and fat tissue, potentially causing individuals, even younger ones, to become frail rather than just improving their body composition.
- This systematic review will evaluate the impact of nutritional supplements on maintaining lean mass during weight loss, particularly when exercise isn't an option.
- The findings will follow PRISMA standards and will be published in a peer-reviewed journal, marking a significant contribution to understanding nutritional support during weight loss.
Article Synopsis
- Sodium-glucose co-transporter 2 inhibitors (SGLT2i), particularly dapagliflozin, are believed to improve weight loss, cardiovascular health, and glycaemic control, though their effects on physical function are unclear.
- The Dapagliflozin, Exercise Training and PhysicAl Function trial will compare the effects of dapagliflozin alone, dapagliflozin with exercise, and diet control on physical function in adults with type 2 diabetes and low physical fitness.
- The study will analyze various outcomes over 24 weeks, including physical performance, cardiac function, and metabolic health, and has received ethical approval for its research methods.
Aims: To design a regional clinical service for people with early-onset type 2 diabetes (EOT2D) in Leicester, Leicestershire and Rutland (England).
Methods: A literature search was undertaken to identify important considerations. A working group of key stakeholders was formed to design a triage system and service pathway.
Article Synopsis
- This scoping review focused on physical activity and sedentary behavior interventions for individuals with frailty and multiple long-term conditions (MLTCs), including their caregivers.
- Researchers examined ten databases from 2000 to October 2023, ultimately retaining 155 papers from 144 studies, most of which were randomized controlled trials with participants averaging 73 years old.
- The findings highlighted that most interventions centered on structured exercise, had a high adherence rate, and yielded positive outcomes, but emphasized the need for more research on habitual activity, caregiver involvement, and a deeper understanding of individual characteristics like MLTCs and ethnicity.
Article Synopsis
- The study aimed to investigate the incidence and rates of sleep disorders over five years in younger adults (16-≤40 years) and middle-older adults (≥40 years) with and without newly diagnosed type 2 diabetes.
- The results showed that individuals with type 2 diabetes had a significantly higher risk of developing sleep disorders compared to those without, with 14.2% of younger and 18.5% of middle-older adults affected.
- The findings suggest that while middle-older adults had a higher absolute risk, younger adults exhibited greater relative rates of sleep disorders, indicating the need for integrated sleep assessments in diabetes management, especially for those aged 40 and under.