BREAST CANCER AND DIAGNOSTIC METHODS: UNDERSTANDING THE ROLE OF BRCA1 AND BRCA2.

Breast cancer is a disease that has a 1 in 8 lifetime risk for women, making it an international burden. Although breast cancer mostly affects women, men have a lifetime risk of around 1 in 1000. The majority of breast cancer instances continue linked to breast cancers that have acquired somatic mutations during a person's lifespan.

Persistent organic pollutants and fatty acids in humpback whales: Antarctic and Chilean feeding and Brazilian breeding sites.

This study investigated the fatty acid composition and persistent organic pollutant (POP) levels in humpback whales across the Southern Ocean, Chilean and Brazilian coast. We found significant regional variations in both fatty acids and POPs. Whales from the Strait of Magellan exhibited a distinct fatty acid profile, indicative of a specialized diet rich in higher trophic level prey.

Dairy farmers' satisfaction with the price paid by processors in competitive markets.

Price is the main attribute considered in negotiations between companies in many agricultural commodity markets. However, there is evidence that unit price is only one factor affecting dairy farmers' satisfaction with dairy processors, which has implications for the coordination of supply chains. The understanding of price satisfaction as embodying multidimensional attributes that influence farmer satisfaction are important for the formulation of commercial strategies aimed at reducing market asymmetries.

Sleep medicine and chronobiology education among Brazilian medical students.

Chronobiology and sleep medicine are pivotal disciplines for understanding human health. Additionally, the lack of training in medical schools exacerbates the underdiagnosis and undertreatment of sleep disorders. This study investigated the exposure of Brazilian medical students to chronobiology and sleep medicine during their undergraduate education and assessed their knowledge in these areas.

Omega-3 Fatty Acids Weaken Lymphocyte Inflammatory Features and Improve Glycemic Control in Nonobese Diabetic Goto-Kakizaki Rats.

Background/objectives: Goto-Kakizaki (GK) rats exhibit insulin resistance and type 2 diabetes mellitus (T2DM) without obesity. This study explored the effects of ω-3 fatty acid supplementation on T lymphocyte polarization in Wistar (WT) and GK rats.

Methods: They were administered ω-3 fatty acid-rich fish oil (FO) containing eicosapentaenoic (540 mg/g) and docosahexaenoic acids (100 mg/g) by oral gavage at 2 g/kg, thrice a week for 8 weeks.