Successful Endoscopic Drainage of Acute Duodenal Diverticulitis Complicated by Abscess.

Duodenal diverticulitis complicated by abscess formation is a rare clinical entity, albeit may, in some cases, be associated with significant morbidity and mortality. We present a unique case that elucidates the success of endoscopic management of duodenal diverticulitis complicated by an abscess in the third part of the duodenum, through forward-viewing endoscopic maneuvers. Although surgery has been the primary interventional strategy for complicated duodenal diverticulitis beyond medical management, endoscopy is shown to be a safe and effective alternative in the clinically stable patient and/or poor surgical candidate, for this uncommon sequela of duodenal diverticulosis.

Flavan-3-ols and Vascular Health: Clinical Evidence and Mechanisms of Action.

Cardiovascular diseases (CVDs) are one of the main causes of mortality and morbidity worldwide. A healthy diet rich in plant-derived compounds such as (poly)phenols appears to have a key role in improving cardiovascular health. Flavan-3-ols represent a subclass of (poly)phenols of great interest for their possible health benefits.

Endoscopic Deployment of Cardiac Septal Occluder Device to Close an Enterovaginal Fistula.

Enterovaginal fistulas (EF) are a rare, pathologic connection between the small bowel and vagina. EF commonly present with abnormal passage of stool, flatus, and purulence through the vaginal orifice, leading to increased risk of severe infections, and cause extreme discomfort for patients. A 70-year-old woman with a history of urothelial carcinoma was treated surgically, resulting in a persistent symptomatic EF.

Comprehensive Review of Aflatoxin and Ochratoxin A Dynamics: Emergence, Toxicological Impact, and Advanced Control Strategies.

Filamentous fungi exhibit remarkable adaptability to diverse substrates and can synthesize a plethora of secondary metabolites. These metabolites, produced in response to environmental stimuli, not only confer selective advantages but also encompass potentially deleterious mycotoxins. Mycotoxins, exemplified by those originating from , , , and species, represent challenging hazards to both human and animal health, thus warranting stringent regulatory control.

Manuka honey's anti-metastatic impact on colon cancer stem-like cells: unveiling its effects on epithelial-mesenchymal transition, angiogenesis and telomere length.

Colorectal cancer often leads to metastasis, with cancer stem cells (CSCs) playing a pivotal role in this process. Two closely linked mechanisms, epithelial-mesenchymal transition and angiogenesis, contribute to metastasis and recent research has also highlighted the impact of telomere replication on this harmful tumor progression. Standard chemotherapy alone can inadvertently promote drug-resistant CSCs, posing a challenge.