Enantiornithes are the most successful early-diverging avian clade, their fossils revealing important information regarding the structure of Cretaceous avifaunas and the parallel refinement of flight alongside the ornithuromorph lineage that includes modern birds. The most diverse recognized family of Early Cretaceous enantiornithines is the Bohaiornithidae, known from the Jehol Biota in northeastern China. Members of this clade enhance our understanding of intraclade morphological diversity and elucidate the independent evolution of this unique lineage.
View Article and Find Full Text PDFNeuroendocrine carcinomas are rare and aggressive malignancies, often diagnosed at advanced stages, leading to poor prognosis. Platinum-based chemotherapy is the standard first-line treatment for advanced neuroendocrine carcinomas; however after achieving response no consensus exists on maintenance therapies and the results are inconsistent. This review examines the role of maintenance therapy following response to first-line chemotherapy in gastroenteropancreatic neuroendocrine carcinomas.
View Article and Find Full Text PDFJ Am Med Dir Assoc
December 2024
Objectives: To investigate pre- and post-pandemic demographic profiles of attendees at adult day care (ADC) facilities in the US South, and survey providers for their experience during the pandemic.
Design: Retrospective analysis and prospective interviews and survey.
Setting And Participants: We received administrative data for South Carolina Medicaid recipients in 2019 (pre-pandemic, n = 21,969) and 2022 (post-pandemic, n = 25,118), prospectively interviewed 6 facility owners and surveyed 62 of 82 ADC facilities in South Carolina (75.
Proc Natl Acad Sci U S A
December 2024
Climate change has emerged as a key threat to biodiversity, leading to broad-scale shifts in distributions of marine and terrestrial species as they attempt to track thermally suitable habitat. By contrast, our understanding of climate responses of freshwater species is relatively undeveloped, limiting our knowledge of whether projected warming will lead to freshwater biodiversity loss. Here, we linked a multicontinental database of riverine fish population abundance time series collected from 1958 to 2019 to temperature data from the same period.
View Article and Find Full Text PDFObjectives: We aim to investigate the time toxicity of patients with gastroenteropancreatic neuroendocrine tumours treated with Lutetium-177 Dotatate in a single institution.
Design: This is a retrospective cohort study.
Methods: All patients with gastroenteropancreatic neuroendocrine tumours treated with Lutetium-177 Dotatate at the Alexander Fleming Institute were included.