The pivotal role of sleep in mediating the effects of life stressors and healthy habits on allostatic load in mid-life adults.

Objectives: We assessed the modulation of allostatic load (AL) by engagement in healthy habits and life stressors, mediated through resilience and the perceived influence of the stressors. Sleep was included as third mediator given extensive evidence associating to all the analysed factors.

Methods: Structural equation models to assess the modulation of AL by either traumatic or psychosocial stressors and healthy habits were generated with data from 620 mid-life adults (age 51.

Comparison of gene expression and polycyclic aromatic compound profiles in hepatic tissue of black guillemot (Cepphus grylle) collected from an oil spill site and a non-spill site in the Arctic.

Economic development, marine transportation, and oil exploration are all activities that are increasing in the Arctic region, and there is concern regarding increased oil-related contaminants entering this sensitive environment. Polycyclic aromatic compounds (PACs) are the main chemical constituents in oil-related contaminants and have been detected in wildlife species following both acute and chronic exposure. In 2020, an oil spill occurred in Kaikopok Bay near Postville, NL, Canada.

Changing practices, procedures, and perceptions: A multi-year person-centered planning initiative in group homes for residents with intellectual and developmental disabilities.

Person-centered planning has been shown to benefit people with disabilities and their quality of life. However, we have little knowledge of how person-centered planning can benefit staff and administration within a group home organization, as well as the extent to which it results in changes to organizational practices and procedures, as well as perceptions of people with disabilities. In this qualitative study, we explored the perspectives of organizational employees, an affiliating behavioral consultant, and residents with intellectual and developmental disabilities, taking into consideration key insights from person-centered planning consultant-coaches, to understand the effects of a person-centered planning initiative on the group home organization.

The effect of Amyloid and Tau Co-pathology on disease progression in Lewy body dementia: A systematic review.

Co-morbid Alzheimer's disease (AD) pathology (amyloid-beta and tau) is commonly observed in Lewy body dementia (LBD), and this may affect clinical outcomes. A systematic review of the effect of AD co-pathology on longitudinal clinical outcomes in LBD was conducted. A search of MEDLINE and EMBASE (October 2024) yielded n = 3558 records that were screened by two independent reviewers.