A mathematical language for linking fine-scale structure in spikes from hundreds to thousands of neurons with behaviour.

Recent advances in neural recording technology allow simultaneously recording action potentials from hundreds to thousands of neurons in awake, behaving animals. However, characterizing spike patterns in the resulting data, and linking these patterns to behaviour, remains a challenging task. The lack of a rigorous mathematical language for variable numbers of events (spikes) emitted by multiple agents (neurons) is an important limiting factor.

Accurate neural control of a hand prosthesis by posture-related activity in the primate grasping circuit.

Brain-computer interfaces (BCIs) have the potential to restore hand movement for people with paralysis, but current devices still lack the fine control required to interact with objects of daily living. Following our understanding of cortical activity during arm reaches, hand BCI studies have focused primarily on velocity control. However, mounting evidence suggests that posture, and not velocity, dominates in hand-related areas.

Application of the Self-Assembling Peptide Hydrogel RADA16 for Hemostasis during Tonsillectomy: A Feasibility Study.

Tonsillectomy is a common surgical procedure but carries a high risk of readmission for secondary bleeding and pain. This study evaluated the feasibility and effectiveness of using the hemostatic self-assembling peptide hydrogel RADA16 (PuraBond, 3-D Matrix SAS; Caluire et Cuire, France) to control bleeding from the tonsillectomy wound bed. Readmission/re-operation rates were compared between a prospective case series of 21 primarily adult tonsillectomy patients treated with topical RADA16 and an untreated historical Control group of 164 patients who underwent tonsillectomy by 10 surgeons at a single tertiary hospital in the UK between March 2019 and June 2022.