Publications by authors named "J A McGiven"
Background: Brucellosis remains a significant health and economic challenge for livestock and humans globally. Despite its public health implications, the factors driving the endemic persistence of at the human-livestock interface in Tanzania remain poorly elucidated. This study aimed to identify the seroprevalence of infection in livestock and humans within a ranching system and determine associated risk factors for disease endemicity.
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- A new zoonotic bacteria is emerging as the primary cause of canine brucellosis in Europe, leading to reproductive issues in dogs and potential chronic illnesses in humans.* -
- Current understanding of host interactions and effective diagnostic tools for this infection is limited, with no vaccine available and ineffective antimicrobial treatments increasing the risk of antibiotic resistance.* -
- The lack of systematic surveillance and legal frameworks to address canine brucellosis complicates management efforts, prompting the need for improved strategies to combat this disease among pets and in kennel settings.*
Article Synopsis
- Bacteria from the genus Brucella cause brucellosis, a serious disease affecting both animals and humans, and have been controversially merged with other unrelated bacterial species based on genomic findings.
- Researchers argue this merger is inappropriate due to lack of thorough phylogenetic analysis and exclusion of expert opinions in brucellosis.
- They warn that combining these groups could lead to confusion and risks in public health, particularly impacting those dealing with brucellosis in under-resourced regions, and call for keeping the Brucella genus distinct.
Brucellosis imposes substantial impacts on livestock production and public health worldwide. A stochastic, age-structured model incorporating herd demographics was developed describing within- and between-herd transmission of in dairy cattle herds. The model was fitted to data from a cross-sectional study conducted in Punjab State of India and used to evaluate the effectiveness of control strategies under consideration.
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