Publications by authors named "J A Lopez Mondejar"
Introduction And Objective: Healthcare resources optimization is crucial to assume the growing demand of neovascular age-related macular degeneration (nAMD). This work provides guidelines and support so that each hospital can lead its change management.
Methods: The OPTIMUS project (n=10 hospitals) was based on face-to-face interviews with the key staff of the ophthalmology services, and alignment with the main responsible for each centre (nominal group) to identify potential needs for improving nAMD.
Objectives: To evaluate effectiveness and safety of certolizumab pegol (CZP) in uveitis due to immune-mediated inflammatory diseases (IMID).
Methods: Multicentre study of CZP-treated patients with IMID uveitis refractory to conventional immunosuppressant. Effectiveness was assessed through the following ocular parameters: best-corrected visual acuity, anterior chamber cells, vitritis, macular thickness and retinal vasculitis.
Article Synopsis
- Non-infectious uveitis is a complex condition that can be debilitating, often treated with immunosuppressive drugs, either alone or in combination, though the effectiveness of these strategies has not been directly compared.
- The CoTHEIA study is a significant research project designed to evaluate the safety, efficacy, and cost-effectiveness of methotrexate, adalimumab, and their combination in treating non-infectious non-anterior uveitis, involving 192 participants over a 52-week period.
- Ethical approvals are in place for the study, which will also employ machine learning to identify patient subgroups based on treatment response, and there are plans to widely disseminate the findings to various stakeholders.
Purpose: To measure thrombopoietin (TPO) levels in the serum and aqueous humors of patients with noninfectious acute anterior uveitis.
Methods: A prospective, comparative, controlled study. Serum and aqueous humors were obtained from the eyes of 16 patients with noninfectious acute anterior uveitis.
We consider deep inelastic scattering in the 't Hooft model. Being solvable, this model allows us to directly compute the moments associated with the cross section at next-to-leading order in the 1/Q(2) expansion. We perform the same computation using the operator-product expansion.
View Article and Find Full Text PDF